Isopeptidase T (long form), human recombinant | 4862

Isopeptidase T is a ubiquitin-specific processing protease (UBP) that specifically disassembles free K48-linked polyubiquitin chains into ubiquitin monomers. There are two human isopeptidase T isoforms; Isopeptidase T short form (isoT-S) and Isopeptidase T long form (isoT-L) which differ by an insertion of 23 amino acids in isoT-L. Isopeptidase T is the only UBP known to require zinc binding to be active.

4862 | Isopeptidase T long form human recombinant DataSheet

Biomolecule/Target: N/A

Synonyms: USP5; Ubiquitin-specific protease 5

Alternates names: USP5; Ubiquitin-specific protease 5

Taglines: A ubiquitin-specific processing protease

NCBI Gene ID #: 20296

NCBI Gene Symbol: MCP-1

Gene Source: Human

Accession #: P10148

Recombinant: Yes

Source: E. coli

Purity by SDS-PAGEs: 98%

Assay: SDS-PAGE

Purity: N/A

Assay #2: HPLC

Endotoxin Level: N/A

Activity (Specifications/test method): N/A

Biological activity: Determined by measuring the dose dependent chemotaxis with human THP-1 cells. The ED is in the range of 1-10 ng/ml.

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 97.0 kDa

Concentration: 0.4 mg/ml

Appearance: Liquid

Physical form description: Supplied at a concentration of 0.4 mg/ml in 50 mM Tris, 10 Mmn -mercaptoethanol, pH 7.5.

Reconstitution Instructions:

Amino acid sequence: