KCNMB2 Antibody | 13-551

KCNMB2 Antibody | 13-551 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 68-194 of human KCNMB2 (NP_005823.1) .

Research Area: Neuroscience

Tested Application: WB, IHC

Application: WB: 1:500 - 1:2000
IHC: 1:50 - 1:200

Specificiy: N/A

Positive Control 1: Mouse kidney

Positive Control 2: Mouse brain

Positive Control 3: Mouse lung

Positive Control 4: Rat brain

Positive Control 5: Rat kidney

Positive Control 6: N/A

Molecular Weight: Observed: 30kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: calcium-activated potassium channel subunit beta-2, BK channel beta subunit 2, BK channel subunit beta-2, MaxiK channel beta 2 subunit, MaxiK channel beta-subunit 2, big potassium channel beta subunit 2, charybdotoxin receptor subunit beta-2, hCG1646471, hbeta2, k (VCA) beta-2, large conductance calcium-activated potassium channel beta 2 subunit, large-conductance Ca2+-activated K+ channel beta2 subunit, potassium channel subfamily M regulatory beta subunit 2, potassium large conductance calcium-activated channel, subfamily M, beta member 2, slo-beta-2

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which decreases the activation time of MaxiK alpha subunit currents. Alternative splicing results in multiple transcript variants of this gene. Additional variants are discussed in the literature, but their full length nature has not been described.