Description
KCNMB2 Antibody | 13-551 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 68-194 of human KCNMB2 (NP_005823.1) .
Research Area: Neuroscience
Tested Application: WB, IHC
Application: WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
Specificiy: N/A
Positive Control 1: Mouse kidney
Positive Control 2: Mouse brain
Positive Control 3: Mouse lung
Positive Control 4: Rat brain
Positive Control 5: Rat kidney
Positive Control 6: N/A
Molecular Weight: Observed: 30kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: calcium-activated potassium channel subunit beta-2, BK channel beta subunit 2, BK channel subunit beta-2, MaxiK channel beta 2 subunit, MaxiK channel beta-subunit 2, big potassium channel beta subunit 2, charybdotoxin receptor subunit beta-2, hCG1646471, hbeta2, k (VCA) beta-2, large conductance calcium-activated potassium channel beta 2 subunit, large-conductance Ca2+-activated K+ channel beta2 subunit, potassium channel subfamily M regulatory beta subunit 2, potassium large conductance calcium-activated channel, subfamily M, beta member 2, slo-beta-2
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which decreases the activation time of MaxiK alpha subunit currents. Alternative splicing results in multiple transcript variants of this gene. Additional variants are discussed in the literature, but their full length nature has not been described.