KW-2478 | B2188

KW-2478 is a potent non-ansamycin heat-shock protein 90 (HspP90) inhibitor (IC₅₀ = 3.8 nM). Displays potent anticancer activity.

KW-2478 is a potent non-ansamycin heat-shock protein 90 (HspP90) inhibitor (IC₅₀ = 3.8 nM). Displays potent anticancer activity.

B2188 | KW-2478 DataSheet

Alternate Name/Synonyms: 2-(2-ethyl-3,5-dihydroxy-6-(3-methoxy-4-(2-morpholinoethoxy)benzoyl)phenyl)-N,N-bis(2-methoxyethyl)acetamide

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 819812-04-9

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₃₀H₄₂N₂O₉

Molecular Weight: 574.66

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent heat-shock protein 90 (HspP90) inhibitor

MDL Number: N/A

PubChem CID: 23116322

SMILES: CCC1=C(C=C(C(=C1CC(=O)N(CCOC)CCOC)C(=O)C2=CC(=C(C=C2)OCCN3CCOCC3)OC)O)O

InChi: InChI=1S/C30H42N2O9/c1-5-22-23(19-28(35)32(11-13-37-2)12-14-38-3)29(25(34)20-24(22)33)30(36)21-6-7-26(27(18-21)39-4)41-17-10-31-8-15-40-16-9-31/h6-7,18,20,33-34H,5,8-17,19H2,1-4H3

InChi Key: VFUXSYAXEKYYMB-UHFFFAOYSA-N