Description
KW-2478 is a potent non-ansamycin heat-shock protein 90 (HspP90) inhibitor (IC₅₀ = 3.8 nM). Displays potent anticancer activity.
KW-2478 is a potent non-ansamycin heat-shock protein 90 (HspP90) inhibitor (IC₅₀ = 3.8 nM). Displays potent anticancer activity.
Alternate Name/Synonyms: 2-(2-ethyl-3,5-dihydroxy-6-(3-methoxy-4-(2-morpholinoethoxy)benzoyl)phenyl)-N,N-bis(2-methoxyethyl)acetamide
Appearance: Crystalline solid
Formulation: N/A
CAS Number: 819812-04-9
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₃₀H₄₂N₂O₉
Molecular Weight: 574.66
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent heat-shock protein 90 (HspP90) inhibitor
MDL Number: N/A
PubChem CID: 23116322
SMILES: CCC1=C(C=C(C(=C1CC(=O)N(CCOC)CCOC)C(=O)C2=CC(=C(C=C2)OCCN3CCOCC3)OC)O)O
InChi: InChI=1S/C30H42N2O9/c1-5-22-23(19-28(35)32(11-13-37-2)12-14-38-3)29(25(34)20-24(22)33)30(36)21-6-7-26(27(18-21)39-4)41-17-10-31-8-15-40-16-9-31/h6-7,18,20,33-34H,5,8-17,19H2,1-4H3
InChi Key: VFUXSYAXEKYYMB-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |