Additional Information
Short Description: |
FLT3, TrkA kinase inhibitor |
Research Area: |
Cell Signaling, Cancer, Apoptosis, Cancer Growth Inhibitors, Tyrosine Kinase Inhibitors |
Alternative Name(s): |
KT5555, CEP-701, (9S,10S,12R)-2,3,9,10,11,12-Hexahydro-10-hydroxy-10-(hydroxymethyl)-9-methyl-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocin-1-one |
Category: |
Small Molecules |
Product Type: |
Inhibitor |
CAS No.: |
111358-88-4 |
Molecular Formula: |
C26H21N3O4 |
Molecular Weight: |
439,5 |
Source: |
Synthetic |
Purity: |
≥98% (HPLC) |
Solubility: |
Soluble to 100 mM in DMSO and to 25 mM in ethanol |
Appearance: |
White powder |
Storage: |
-20ºC |
Shipping: |
Shipped Ambient |
SMILES: |
[C@@]67([N]2C1=C5C(=C4C(=C1C3=C2C=CC=C3)CNC4=O)C8=C([N]5[C@H](O6)C[C@]7(O)CO)C=CC=C8)C |
InChI: |
InChI=1S/C26H21N3O4/c1-25-26(32,12-30)10-18(33-25)28-16-8-4-2-6-13(16)20-21-15(11-27-24(21)31)19-14-7-3-5-9-17(14)29(25)23(19)22(20)28/h2-9,18,30,32H,10-12H2,1H3,(H,27,31)/t18-,25+,26+/m1/s1 |
InChIKey: |
UIARLYUEJFELEN-LROUJFHJSA-N |
Field of Use: |
For in vitro research use only. |
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