LBD
LMCD1 Antibody (C-term) [AMM06311G]
- SKU:
- LBD-AMM06311G
- Availability:
- Usually ships in 5 working days
Description
LMCD1 Antibody (C-term) [AMM06311G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H, M, Rat
Specificity: This LMCD1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 316-350 amino acids from the C-terminal region of human LMCD1.
Cellular Localisation: Cytoplasm. Nucleus. Note=May shuttle between the cytoplasm and the nucleus.
Molecular Weight: 40833
Clone: Polyclonal
Gene Name: LMCD1
Gene ID: 29995
Function: Transcriptional cofactor that restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. Represses GATA6- mediated trans activation of lung- and cardiac tissue-specific promoters. Inhibits DNA-binding by GATA4 and GATA1 to the cTNC promoter (By similarity) . Plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway.
Summary: Tissue Location: Expressed in the heart (at protein level) . Expressed in many tissues with highest abundance in skeletal muscle
Form: N/A
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Application: WB
Dilution: WB--1:1000
Synonyms: LIM and cysteine-rich domains protein 1, Dyxin, LMCD1