LOXL2 Antibody| F44528-0.08ML/F44528-0.4ML/R32365

LOXL2 Antibody| F44528-0.08ML/F44528-0.4ML/R32365 | Gentaur UK, US & Europe Distribution

Background: This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Human

Predicted Spacies Reactivity: Mouse, Rat, Bovine, Chicken

Application: WB, ELISA

Application Details: Western blot: 1:1000

Application Note: Titration of the LOXL2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This LOXL2 antibody is available for research use only.

Purity: Antigen affinity

Immunogen: A portion of amino acids 589-617 from the human protein was used as the immunogen for this LOXL2 antibody.

Storage: Aliquot the LOXL2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A