Description
Lu AF21934 is a brain-penetrating positive allosteric modulator of the metabotropic glutamate receptor 4 (mGlu4), that reduces the harmaline-induced hyperactivity.
Lu AF21934 is a brain-penetrating positive allosteric modulator of the metabotropic glutamate receptor 4 (mGlu4), that reduces the harmaline-induced hyperactivity.
Alternate Name/Synonyms: (1S,2R)-N1-(3,4-Dichlorophenyl)cyclohexane-1,2-dicarboxamide
Appearance: Crystalline solid
Formulation: N/A
CAS Number: 1445605-23-1
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₄H₁₆Cl₂N₂O₂
Molecular Weight: 315.2
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A brain-penetrating positive allosteric modulator of the metabotropic glutamate receptor 4 (mGlu4)
MDL Number: N/A
PubChem CID: 66553157
SMILES: C1CCC(C(C1)C(=O)N)C(=O)NC2=CC(=C(C=C2)Cl)Cl
InChi: InChI=1S/C14H16Cl2N2O2/c15-11-6-5-8(7-12(11)16)18-14(20)10-4-2-1-3-9(10)13(17)19/h5-7,9-10H,1-4H2,(H2,17,19)(H,18,20)/t9-,10+/m1/s1
InChi Key: AVKZWCJNDWOBAM-ZJUUUORDSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |