LuAF21934 | B1302

Lu AF21934 is a brain-penetrating positive allosteric modulator of the metabotropic glutamate receptor 4 (mGlu4), that reduces the harmaline-induced hyperactivity.

Lu AF21934 is a brain-penetrating positive allosteric modulator of the metabotropic glutamate receptor 4 (mGlu4), that reduces the harmaline-induced hyperactivity.

B1302 | LuAF21934 DataSheet

Alternate Name/Synonyms: (1S,2R)-N1-(3,4-Dichlorophenyl)cyclohexane-1,2-dicarboxamide

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 1445605-23-1

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₄H₁₆Cl₂N₂O₂

Molecular Weight: 315.2

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A brain-penetrating positive allosteric modulator of the metabotropic glutamate receptor 4 (mGlu4)

MDL Number: N/A

PubChem CID: 66553157

SMILES: C1CCC(C(C1)C(=O)N)C(=O)NC2=CC(=C(C=C2)Cl)Cl

InChi: InChI=1S/C14H16Cl2N2O2/c15-11-6-5-8(7-12(11)16)18-14(20)10-4-2-1-3-9(10)13(17)19/h5-7,9-10H,1-4H2,(H2,17,19)(H,18,20)/t9-,10+/m1/s1

InChi Key: AVKZWCJNDWOBAM-ZJUUUORDSA-N