Marizomib | B2493

Marizomib (Salinosporamide A) is a potent, reversible, broad-spectrum, brain-penetrant proteasome inhibitor, that displays antitumor activity in vitro and in vivo.

Marizomib (Salinosporamide A) is a potent, reversible, broad-spectrum, brain-penetrant proteasome inhibitor, that displays antitumor activity in vitro and in vivo.

B2493 | Marizomib DataSheet

Alternate Name/Synonyms: salinosporamide A; (1R,4R,5S)-4-(2-chloroethyl)-1-[(S)-[(1S)-cyclohex-2-en-1-yl]-hydroxymethyl]-5-methyl-6-oxa-2-azabicyclo[3.2.0]heptane-3,7-dione; NPI-0052

Appearance: Crystalline solid

Formulation:

CAS Number: 437742-34-2

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₅H₂₀ClNO₄

Molecular Weight: 313.77

Cell-Permeable?: True

Purity: ≥98%

Solubilities: in DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A broad-spectrum proteasome inhibitor

MDL Number:

PubChem CID: 11347535

SMILES: CC12C(C(=O)NC1(C(=O)O2)C(C3CCCC=C3)O)CCCl

InChi: InChI=1S/C15H20ClNO4/c1-14-10(7-8-16)12(19)17-15(14,13(20)21-14)11(18)9-5-3-2-4-6-9/h3,5,9-11,18H,2,4,6-8H2,1H3,(H,17,19)/t9-,10+,11+,14+,15+/m1/s1

InChi Key: NGWSFRIPKNWYAO-SHTIJGAHSA-N