Description
Marizomib (Salinosporamide A) is a potent, reversible, broad-spectrum, brain-penetrant proteasome inhibitor, that displays antitumor activity in vitro and in vivo.
Marizomib (Salinosporamide A) is a potent, reversible, broad-spectrum, brain-penetrant proteasome inhibitor, that displays antitumor activity in vitro and in vivo.
Alternate Name/Synonyms: salinosporamide A; (1R,4R,5S)-4-(2-chloroethyl)-1-[(S)-[(1S)-cyclohex-2-en-1-yl]-hydroxymethyl]-5-methyl-6-oxa-2-azabicyclo[3.2.0]heptane-3,7-dione; NPI-0052
Appearance: Crystalline solid
Formulation:
CAS Number: 437742-34-2
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₅H₂₀ClNO₄
Molecular Weight: 313.77
Cell-Permeable?: True
Purity: ≥98%
Solubilities: in DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A broad-spectrum proteasome inhibitor
MDL Number:
PubChem CID: 11347535
SMILES: CC12C(C(=O)NC1(C(=O)O2)C(C3CCCC=C3)O)CCCl
InChi: InChI=1S/C15H20ClNO4/c1-14-10(7-8-16)12(19)17-15(14,13(20)21-14)11(18)9-5-3-2-4-6-9/h3,5,9-11,18H,2,4,6-8H2,1H3,(H,17,19)/t9-,10+,11+,14+,15+/m1/s1
InChi Key: NGWSFRIPKNWYAO-SHTIJGAHSA-N
Additional Information
Storage Condition: |
-20ºC |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |