BW
MATK/Lsk (V157) polyclonal Antibody | BS9181
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- BW-BS9181
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- Usually ships in 5 working days
Description
MATK/Lsk (V157) polyclonal Antibody | BS9181 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB IHC
Application Range: WB: 1:500~1:1000 IHC: 1:50~1:200
Background: For instance, a mutant of c-Src, in which Y527 is replaced by phenylalanine, is transforming and displays 5 to 10-fold elevated kinase activity compared to its normal counterpart. Csk has been identified as a Src related tyrosine kinase having both SH2 and SH3 domains and a catalytic domain but lacking sequences amino terminal to the SH3 domain as well as the carboxy-terminal regulatory sequences. Csk phosphorylates Src on Y527 and also down regulates Lyn, Fyn and Lck by tyrosine phosphorylation of carboxy-terminal regulatory sites. A Csk-like protein- tyrosine kinase of mouse origin (Ctk), also designated Ntk, and its human homolog, Lsk, have also been described.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: Lsk (V157) polyclonal Antibody detects endogenous levels of Lsk protein.
Molecular Weight: ~ 56 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Megakaryocyte-associated tyrosine-protein kinase; CSK homologous kinase; CHK; Hematopoietic consensus tyrosine-lacking kinase; Protein kinase HYL; Tyrosine-protein kinase CTK; MATK; CTK; HYL
Immunogen: Synthetic peptide, corresponding to amino acids 140-180 of Human Lsk.
Conjugate: N/A
Modification: N/A
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: N/A