MCA-YVADAPK(Dnp)-OH | B2717

MCA-YVADAP-K(Dnp)-OH is a fluorogenic substrate for caspase-1 and angiotensin-converting enzyme 2 (ACE2). Upon cleavage by caspase-1 or ACE2, 7-methoxycoumarin-4-acetyl (MCA) is released and its fluorescence can be used to estimate enzyme activity. MCA displays excitation/emission maxima of 328/420 nm, respectively.

MCA-YVADAP-K(Dnp)-OH is a fluorogenic substrate for caspase-1 and angiotensin-converting enzyme 2 (ACE2). Upon cleavage by caspase-1 or ACE2, 7-methoxycoumarin-4-acetyl (MCA) is released and its fluorescence can be used to estimate enzyme activity. MCA displays excitation/emission maxima of 328/420 nm, respectively.

B2717 | MCA-YVADAPK(Dnp)-OH DataSheet

Alternate Name/Synonyms: Mca-Tyr-Val-Ala-Asp-Ala-Pro-Lys(Dnp)-OH.,Caspase-1 substrate,ACE2 substrate

Appearance: White to yellow solid

Formulation:

CAS Number: N/A

Structure Available?: No

Peptide sequence: Mca-Tyr-Val-Ala-Asp-Ala-Pro-Lys(Dnp)-OH

Salt Form:

Molecular Formula: C₅₃H₆₄N₁₀O₁₉

Molecular Weight: 1145.1

Cell-Permeable?: TRUE

Purity: ≥95% by HPLC

Solubilities: >5 mg/ml DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A caspase-1 and ACE2 substrate

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