MCL1 Antibody| F42742-0.08ML/F42742-0.4ML/R31553

MCL1 Antibody| F42742-0.08ML/F42742-0.4ML/R31553 | Gentaur UK, US & Europe Distribution

Background: The Mcl-1 protein belongs to the Bcl-2 family. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. The longer gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene product (isoform 2) promotes apoptosis and is death-inducing.

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Human, Mouse

Predicted Spacies Reactivity: N/A

Application: IHC, FACS, WB, ELISA

Application Details: Western blot: 1:1000, IHC (Paraffin): 1:10-1:50, Flow Cytometry: 1:10-1:50

Application Note: Titration of the MCL1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This MCL1 antibody is available for research use only.

Purity: Purified

Immunogen: A portion of amino acids 191-226 from the human protein was used as the immunogen for this MCL1 antibody.

Storage: Aliquot the MCL1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A