Description
Human macrophage/monocyte chemotactic protein-4 (MCP-4) is a member of the chemokine family (C-C) of cytokines. Like eotaxin, MCP-4 is a powerful eosinophil chemoattractant. Additionally, like MCP-3, MCP-4 elicits chemoattraction of monocytes and T lymphocytes. MCP-4 is a peptide of 8.6 kDa that consists of 75 amino acid residues.
4231 | MCP-4 human recombinant DataSheet
Biomolecule/Target: MCP-4
Synonyms: Monocyte Chemotactic Protein-4, CCL13, NCC-1
Alternates names: SYM1, SYNS1, NOG.
Taglines: Chemoattractant for monocytes
NCBI Gene ID #: 9241
NCBI Gene Symbol: NOG
Gene Source: Human
Accession #: Q13253
Recombinant: Yes
Source: Human 293 cell expressed
Purity by SDS-PAGEs: > 95%
Assay: SDS-PAGE
Purity: 95%
Assay #2: HPLC
Endotoxin Level: < 1.0 EU per 1 g of protein
Activity (Specifications/test method): N/A
Biological activity: ED is typically 20 to 100 ng/mL. The specific activity was determined by the dose-dependent inhibition of rhBMP4 induced alkaline phosphate production by ATDC5 cells.
Results: 20 to 100 ng/ml
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 65 kDa, homodimer, glycosylated
Concentration: N/A
Appearance: Lyophilized protein
Physical form description: Sterile filtered and then lyophilized from a concentrated (1mg/ml) sterile solution containing 20 mM phosphate buffer, pH 7.4 and 130 mM NaCl.
Reconstitution Instructions: Reconstitute in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.
Amino acid sequence: N/A