MCP-4, human recombinant | 4231

Human macrophage/monocyte chemotactic protein-4 (MCP-4) is a member of the chemokine family (C-C) of cytokines. Like eotaxin, MCP-4 is a powerful eosinophil chemoattractant. Additionally, like MCP-3, MCP-4 elicits chemoattraction of monocytes and T lymphocytes. MCP-4 is a peptide of 8.6 kDa that consists of 75 amino acid residues.

4231 | MCP-4 human recombinant DataSheet

Biomolecule/Target: MCP-4

Synonyms: Monocyte Chemotactic Protein-4, CCL13, NCC-1

Alternates names: SYM1, SYNS1, NOG.

Taglines: Chemoattractant for monocytes

NCBI Gene ID #: 9241

NCBI Gene Symbol: NOG

Gene Source: Human

Accession #: Q13253

Recombinant: Yes

Source: Human 293 cell expressed

Purity by SDS-PAGEs: > 95%

Assay: SDS-PAGE

Purity: 95%

Assay #2: HPLC

Endotoxin Level: < 1.0 EU per 1 g of protein

Activity (Specifications/test method): N/A

Biological activity: ED is typically 20 to 100 ng/mL. The specific activity was determined by the dose-dependent inhibition of rhBMP4 induced alkaline phosphate production by ATDC5 cells.

Results: 20 to 100 ng/ml

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 65 kDa, homodimer, glycosylated

Concentration: N/A

Appearance: Lyophilized protein

Physical form description: Sterile filtered and then lyophilized from a concentrated (1mg/ml) sterile solution containing 20 mM phosphate buffer, pH 7.4 and 130 mM NaCl.

Reconstitution Instructions: Reconstitute in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.

Amino acid sequence: N/A