LBD
MCT1 (SLC16A1) Antibody (C-term) [APR31985G]
- SKU:
- LBD-APR31985G
- Availability:
- Usually ships in 5 working days
Description
MCT1 (SLC16A1) Antibody (C-term) [APR31985G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This MCT1 (SLC16A1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 430-460 amino acids from the C-terminal region of human MCT1 (SLC16A1) .
Cellular Localisation: Cell membrane; Multi-pass membrane protein
Molecular Weight: 53944
Clone: Polyclonal
Gene Name: SLC16A1
Gene ID: 6566
Function: Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Depending on the tissue and on cicumstances, mediates the import or export of lactic acid and ketone bodies. Required for normal nutrient assimilation, increase of white adipose tissue and body weight gain when on a high-fat diet. Plays a role in cellular responses to a high-fat diet by modulating the cellular levels of lactate and pyruvate, small molecules that contribute to the regulation of central metabolic pathways and insulin secretion, with concomitant effects on plasma insulin levels and blood glucose homeostasis.
Summary: Tissue Location: Detected in heart and in blood lymphocytes and monocytes (at protein level) . Widely expressed
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB
Dilution: WB--1:1000
Synonyms: Monocarboxylate transporter 1, MCT 1, Solute carrier family 16 member 1, SLC16A1, MCT1