Mdivi -1 | 2441

Cell-permeable. A selective inhibitor of Dnm1 GTPase (IC₅₀ =1-10 µM). Inhibits mitochondrial outer membrane permeabilization. Inhibits mitochondrial division and apoptosis.

Mdivi-1 is a selective inhibitor of Dnm1 GTPase (IC₅₀ =1-10 µM). Inhibits mitochondrial outer membrane permeabilization. Inhibits mitochondrial division and apoptosis.

2441 | Mdivi -1 DataSheet

Alternate Name/Synonyms: 3-(2,4-Dichloro-5-methoxyphenyl)-2-sulfanyl-4(3H)-quinazolinone

Appearance: White solid

Formulation: N/A

CAS Number: 338967-87-6

Structure Available?: Yes

Peptide sequence: No

Salt Form: No

Molecular Formula: C₁₅H₁₀Cl₂N₂O₂S

Molecular Weight: 353.23

Cell-Permeable?: Yes

Purity: ≥98% by TLC

Solubilities: DMSO (~25 mg/ml)

Handling: Protect from light and air

Country of Origin: USA

Tag Line: A mitochondrial division inhibitor

MDL Number: MFCD00974506

PubChem CID: 3825829

SMILES: COC1=C(C=C(C(=C1)N2C(=O)C3=CC=CC=C3NC2=S)Cl)Cl

InChi: InChI=1S/C15H10Cl2N2O2S/c1-21-13-7-12(9(16)6-10(13)17)19-14(20)8-4-2-3-5-11(8)18-15(19)22/h2-7H,1H3,(H,18,22)

InChi Key: NZJKEVWTYMOYOR-UHFFFAOYSA-N