MF-438 | B1178

MF-438 is a potent, cell-permeable inhibitor of Stearoyl-CoA Desaturase 1 (SCD1) with an IC₅₀ of 2.3 nM.

MF-438 is a potent, cell-permeable inhibitor of Stearoyl-CoA Desaturase 1 (SCD1) with an IC₅₀ of 2.3 nM.

B1178 | MF-438 DataSheet

Alternate Name/Synonyms: 2-methyl-5-(6-(4-(2-(trifluoromethyl)phenoxy)piperidin-1-yl)pyridazin-3-yl)-1,3,4-thiadiazole

Appearance: Off-white solid

Formulation: N/A

CAS Number: 921605-87-0

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: N/A

Molecular Formula: C₁₉H₁₈F₃N₅OS

Molecular Weight: 421.44

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (~5 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent, cell-permeable inhibitor of Stearoyl-CoA Desaturase 1 (SCD1)

MDL Number: N/A

PubChem CID: 16042458

SMILES: CC1=NN=C(S1)C2=NN=C(C=C2)N3CCC(CC3)OC4=CC=CC=C4C(F)(F)F

InChi: InChI=1S/C19H18F3N5OS/c1-12-23-26-18(29-12)15-6-7-17(25-24-15)27-10-8-13(9-11-27)28-16-5-3-2-4-14(16)19(20,21)22/h2-7,13H,8-11H2,1H3

InChi Key: NVUJDKDVOZVALT-UHFFFAOYSA-N