Description
MF-438 is a potent, cell-permeable inhibitor of Stearoyl-CoA Desaturase 1 (SCD1) with an IC₅₀ of 2.3 nM.
MF-438 is a potent, cell-permeable inhibitor of Stearoyl-CoA Desaturase 1 (SCD1) with an IC₅₀ of 2.3 nM.
Alternate Name/Synonyms: 2-methyl-5-(6-(4-(2-(trifluoromethyl)phenoxy)piperidin-1-yl)pyridazin-3-yl)-1,3,4-thiadiazole
Appearance: Off-white solid
Formulation: N/A
CAS Number: 921605-87-0
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: N/A
Molecular Formula: C₁₉H₁₈F₃N₅OS
Molecular Weight: 421.44
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (~5 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent, cell-permeable inhibitor of Stearoyl-CoA Desaturase 1 (SCD1)
MDL Number: N/A
PubChem CID: 16042458
SMILES: CC1=NN=C(S1)C2=NN=C(C=C2)N3CCC(CC3)OC4=CC=CC=C4C(F)(F)F
InChi: InChI=1S/C19H18F3N5OS/c1-12-23-26-18(29-12)15-6-7-17(25-24-15)27-10-8-13(9-11-27)28-16-5-3-2-4-14(16)19(20,21)22/h2-7,13H,8-11H2,1H3
InChi Key: NVUJDKDVOZVALT-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |