MGMT Antibody| F42543-0.08ML/F42543-0.4ML/R31679

MGMT Antibody| F42543-0.08ML/F42543-0.4ML/R31679 | Gentaur UK, US & Europe Distribution

Background: MGMT is involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Human

Predicted Spacies Reactivity: N/A

Application: FACS, WB, ELISA

Application Details: Western blot: 1:1000, Flow Cytometry: 1:10-1:50

Application Note: Titration of the MGMT antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This MGMT antibody is available for research use only.

Purity: Purified

Immunogen: A portion of amino acids 1-30 from the human protein was used as the immunogen for this MGMT antibody.

Storage: Aliquot the MGMT antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A