Description
MHY1485 is an mTOR activator that potently inhibits autophagy by suppression of fusion between autophagosomes and lysosomes. Treatment with MHY1485 suppresses the basal autophagic flux, and this inhibitory effect is clearly confirmed in cells under starvation, a strong physiological inducer of autophagy.
MHY1485 is an mTOR activator that potently inhibits autophagy by suppression of fusion between autophagosomes and lysosomes. Treatment with MHY1485 suppresses the basal autophagic flux, and this inhibitory effect is clearly confirmed in cells under starvation, a strong physiological inducer of autophagy.
Alternate Name/Synonyms: 4,6-Dimorpholino-N-(4-nitrophenyl)-1,3,5-triazin-2-amine
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 326914-06-1
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₇H₂₁N₇O₄
Molecular Weight: 387.39
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (~ 2 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent mTOR activator
MDL Number: N/A
PubChem CID: 2834965
SMILES: C1COCCN1C2=NC(=NC(=N2)NC3=CC=C(C=C3)[N+](=O)[O-])N4CCOCC4
InChi: InChI=1S/C17H21N7O4/c25-24(26)14-3-1-13(2-4-14)18-15-19-16(22-5-9-27-10-6-22)21-17(20-15)23-7-11-28-12-8-23/h1-4H,5-12H2,(H,18,19,20,21)
InChi Key: MSSXBKQZZINCRI-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |