MHY1485 | 9419

MHY1485 is an mTOR activator that potently inhibits autophagy by suppression of fusion between autophagosomes and lysosomes. Treatment with MHY1485 suppresses the basal autophagic flux, and this inhibitory effect is clearly confirmed in cells under starvation, a strong physiological inducer of autophagy.

MHY1485 is an mTOR activator that potently inhibits autophagy by suppression of fusion between autophagosomes and lysosomes. Treatment with MHY1485 suppresses the basal autophagic flux, and this inhibitory effect is clearly confirmed in cells under starvation, a strong physiological inducer of autophagy.

9419 | MHY1485 DataSheet

Alternate Name/Synonyms: 4,6-Dimorpholino-N-(4-nitrophenyl)-1,3,5-triazin-2-amine

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 326914-06-1

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₇H₂₁N₇O₄

Molecular Weight: 387.39

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (~ 2 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent mTOR activator

MDL Number: N/A

PubChem CID: 2834965

SMILES: C1COCCN1C2=NC(=NC(=N2)NC3=CC=C(C=C3)[N+](=O)[O-])N4CCOCC4

InChi: InChI=1S/C17H21N7O4/c25-24(26)14-3-1-13(2-4-14)18-15-19-16(22-5-9-27-10-6-22)21-17(20-15)23-7-11-28-12-8-23/h1-4H,5-12H2,(H,18,19,20,21)

InChi Key: MSSXBKQZZINCRI-UHFFFAOYSA-N