26
Miglustat hydrochloride | B3056
- SKU:
- 26-B3056-GEN
- Availability:
- Usually shipped in 5 working days
Description
Miglustat is an inhibitor of the N-linked oligosaccharide processing enzymes α-glucosidase I and II. It inhibits rat testicular enzymes ceramide-glucosyltransferase and β-glucosidase 2 with IC50 values of 32 and 81 μM respectively. Miglustat is used for the treatment of type 1 Gaucher’s disease. It is an inhibitor of HIV replication in vitro. It shows activity against SARS-CoV-2 in vitro with EC50 values in the micromolar range.
Miglustat is an inhibitor of the N-linked oligosaccharide processing enzymes α-glucosidase I and II. It inhibits rat testicular enzymes ceramide-glucosyltransferase and β-glucosidase 2 with IC50 values of 32 and 81 μM respectively. Miglustat is used for the treatment of type 1 Gaucher’s disease. It is an inhibitor of HIV replication in vitro. It shows activity against SARS-CoV-2 in vitro with EC50 values in the micromolar range.
B3056 | Miglustat hydrochloride DataSheet
Alternate Name/Synonyms: N-Butyldeoxynojirimycin hydrochloride; NB-DNJ, HCl; (2R,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-3,4,5-triol hydrochloride; OGT918
Appearance: White solid
Formulation:
CAS Number: 210110-90-0
Structure Available?: TRUE
Peptide sequence:
Salt Form: TRUE
Molecular Formula: C₁₀H₂₂ClNO₄
Molecular Weight: 255.74
Cell-Permeable?: TRUE
Purity: ≥98%
Solubilities: ~10 mg/ml in DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: An inhibitor of α-glucosidase I and II
MDL Number: MFCD00269940
PubChem CID: 6603107
SMILES: CCCCN1CC(C(C(C1CO)O)O)O.Cl
InChi: InChI=1S/C10H21NO4.ClH/c1-2-3-4-11-5-8(13)10(15)9(14)7(11)6-12;/h7-10,12-15H,2-6H2,1H3;1H/t7-,8+,9-,10-;/m1./s1
InChi Key: QPAFAUYWVZMWPR-ZSOUGHPYSA-N
Additional Information
Storage Condition: |
-20ºC |
Shipping Condition: |
RT |
Shelf Life: |
36 months |