Description
MK-5108 is a highly selective Aurora A inhibitor with IC50 of 0.064 nM
MK-5108 is a highly selective Aurora A inhibitor with IC50 of 0.064 nM
Alternate Name/Synonyms: 4-(3-chloro-2-fluorophenoxy)-1-[[6-(1,3-thiazol-2-ylamino)pyridin-2-yl]methyl]cyclohexane-1-carboxylic acid
Appearance: Solid
Formulation: N/A
CAS Number: 1010085-13-8
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C22H21ClFN3O3S
Molecular Weight: 461.94
Cell-Permeable?: Yes
Purity: >98%
Solubilities: DMSO ≤ 6.4 mg/ml (Need warming)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A highly selective Aurora A inhibitor with IC50 of 0.064 nM
MDL Number: MFCD22124479
PubChem CID: 24748204
SMILES: C1CC(CCC1OC2=C(C(=CC=C2)Cl)F)(CC3=NC(=CC=C3)NC4=NC=CS4)C(=O)O
InChi: 1S/C22H21ClFN3O3S/c23-16-4-2-5-17(19(16)24)30-15-7-9-22(10-8-15,20(28)29)13-14-3-1-6-18(26-14)27-21-25-11-12-31-21/h1-6,11-12,15H,7-10,13H2,(H,28,29)(H,25,26,27)
InChi Key: LCVIRAZGMYMNNT-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |