MK-5108 | B1344

MK-5108 is a highly selective Aurora A inhibitor with IC50 of 0.064 nM

MK-5108 is a highly selective Aurora A inhibitor with IC50 of 0.064 nM

B1344 | MK-5108 DataSheet

Alternate Name/Synonyms: 4-(3-chloro-2-fluorophenoxy)-1-[[6-(1,3-thiazol-2-ylamino)pyridin-2-yl]methyl]cyclohexane-1-carboxylic acid

Appearance: Solid

Formulation: N/A

CAS Number: 1010085-13-8

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C22H21ClFN3O3S

Molecular Weight: 461.94

Cell-Permeable?: Yes

Purity: >98%

Solubilities: DMSO ≤ 6.4 mg/ml (Need warming)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A highly selective Aurora A inhibitor with IC50 of 0.064 nM

MDL Number: MFCD22124479

PubChem CID: 24748204

SMILES: C1CC(CCC1OC2=C(C(=CC=C2)Cl)F)(CC3=NC(=CC=C3)NC4=NC=CS4)C(=O)O

InChi: 1S/C22H21ClFN3O3S/c23-16-4-2-5-17(19(16)24)30-15-7-9-22(10-8-15,20(28)29)13-14-3-1-6-18(26-14)27-21-25-11-12-31-21/h1-6,11-12,15H,7-10,13H2,(H,28,29)(H,25,26,27)

InChi Key: LCVIRAZGMYMNNT-UHFFFAOYSA-N