ML-204 | 9448

ML-204 is a selective blocker of TRPC4 channels. Displays 19-fold selectivity against TRPC6 and 9-fold selectivity against TRPC5; shows no significant activity at TRPV1, TRPV3, TRPA1 and TRPM8 channels even at concentrations up to 22 μM.

ML-204 is a selective blocker of TRPC4 channels. Displays 19-fold selectivity against TRPC6 and 9-fold selectivity against TRPC5; shows no significant activity at TRPV1, TRPV3, TRPA1 and TRPM8 channels even at concentrations up to 22 μM.

9448 | ML-204 DataSheet

Alternate Name/Synonyms: 4-Methyl-2-(1-piperidinyl)quinoline

Appearance: Off-white solid

Formulation: N/A

CAS Number: 5465-86-1

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: N/A

Molecular Formula: C₁₅H₁₈N₂

Molecular Weight: 226.32

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (>20 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A selective blocker of TRPC4 channels.

MDL Number: N/A

PubChem CID: 230710

SMILES: CC1=CC(=NC2=CC=CC=C12)N3CCCCC3

InChi: InChI=1S/C15H18N2/c1-12-11-15(17-9-5-2-6-10-17)16-14-8-4-3-7-13(12)14/h3-4,7-8,11H,2,5-6,9-10H2,1H3

InChi Key: USYRQXDHKXGTCK-UHFFFAOYSA-N