Description
ML-204 is a selective blocker of TRPC4 channels. Displays 19-fold selectivity against TRPC6 and 9-fold selectivity against TRPC5; shows no significant activity at TRPV1, TRPV3, TRPA1 and TRPM8 channels even at concentrations up to 22 μM.
ML-204 is a selective blocker of TRPC4 channels. Displays 19-fold selectivity against TRPC6 and 9-fold selectivity against TRPC5; shows no significant activity at TRPV1, TRPV3, TRPA1 and TRPM8 channels even at concentrations up to 22 μM.
Alternate Name/Synonyms: 4-Methyl-2-(1-piperidinyl)quinoline
Appearance: Off-white solid
Formulation: N/A
CAS Number: 5465-86-1
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: N/A
Molecular Formula: C₁₅H₁₈N₂
Molecular Weight: 226.32
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (>20 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A selective blocker of TRPC4 channels.
MDL Number: N/A
PubChem CID: 230710
SMILES: CC1=CC(=NC2=CC=CC=C12)N3CCCCC3
InChi: InChI=1S/C15H18N2/c1-12-11-15(17-9-5-2-6-10-17)16-14-8-4-3-7-13(12)14/h3-4,7-8,11H,2,5-6,9-10H2,1H3
InChi Key: USYRQXDHKXGTCK-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |