ML-354 | 9415

ML-354 is a selective PAR4 antagonist (IC₅₀ = 140 nM). Displays 71-fold selectivity for PAR4 over PAR1 (PAR-1 IC₅₀ = 10 μM).

ML-354 is a selective PAR4 antagonist (IC₅₀ = 140 nM). Displays 71-fold selectivity for PAR4 over PAR1 (PAR-1 IC₅₀ = 10 μM).

9415 | ML-354 DataSheet

Alternate Name/Synonyms: 1-Methyl-5-nitro-3-phenyl-1H-indole-2-methanol

Appearance: Yellow solid

Formulation: N/A

CAS Number: 89159-60-4

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₆H₁₄N2O₃

Molecular Weight: 282.39

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (~25 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A selective PAR4 antagonist

MDL Number: N/A

PubChem CID: 752812

SMILES: CN1C2=C(C=C(C=C2)[N+](=O)[O-])C(=C1CO)C3=CC=CC=C3

InChi: InChI=1S/C16H14N2O3/c1-17-14-8-7-12(18(20)21)9-13(14)16(15(17)10-19)11-5-3-2-4-6-11/h2-9,19H,10H2,1H3

InChi Key: GNJUKVGDCUKDLF-UHFFFAOYSA-N