Description
ML-354 is a selective PAR4 antagonist (IC₅₀ = 140 nM). Displays 71-fold selectivity for PAR4 over PAR1 (PAR-1 IC₅₀ = 10 μM).
ML-354 is a selective PAR4 antagonist (IC₅₀ = 140 nM). Displays 71-fold selectivity for PAR4 over PAR1 (PAR-1 IC₅₀ = 10 μM).
Alternate Name/Synonyms: 1-Methyl-5-nitro-3-phenyl-1H-indole-2-methanol
Appearance: Yellow solid
Formulation: N/A
CAS Number: 89159-60-4
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₆H₁₄N2O₃
Molecular Weight: 282.39
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (~25 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A selective PAR4 antagonist
MDL Number: N/A
PubChem CID: 752812
SMILES: CN1C2=C(C=C(C=C2)[N+](=O)[O-])C(=C1CO)C3=CC=CC=C3
InChi: InChI=1S/C16H14N2O3/c1-17-14-8-7-12(18(20)21)9-13(14)16(15(17)10-19)11-5-3-2-4-6-11/h2-9,19H,10H2,1H3
InChi Key: GNJUKVGDCUKDLF-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |