ML161 | 2689

ML161 is an allosteric Inhibitor of protease-activated receptor 1 (PAR1)-mediated platelet activation (IC₅₀ = 0.26 μM for the inhibition of platelet P-selectin expression on human platelets). Also inhibits thrombin-induced platelet activation.

ML161 is an allosteric Inhibitor of protease-activated receptor 1 (PAR1)-mediated platelet activation (IC₅₀ = 0.26 μM for the inhibition of platelet P-selectin expression on human platelets). Also inhibits thrombin-induced platelet activation.

2689 | ML161 DataSheet

Alternate Name/Synonyms: 2-Bromo-N-[3-[(1-oxobutyl)amino]phenyl]benzamide

Appearance: Brown solid

Formulation: N/A

CAS Number: 423735-93-7

Structure Available?: Y

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₇H₁₇BrN₂O₂

Molecular Weight: 361.23

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (~ 30 mg/ml) or EtOH (~ 30 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: An allosteric Inhibitor of protease-activated receptor 1 (PAR1)-mediated platelet activation

MDL Number: MFCD03063772

PubChem CID: 1048267

SMILES: CCCC(=O)NC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2Br

InChi: InChI=1S/C17H17BrN2O2/c1-2-6-16(21)19-12-7-5-8-13(11-12)20-17(22)14-9-3-4-10-15(14)18/h3-5,7-11H,2,6H2,1H3,(H,19,21)(H,20,22)

InChi Key: DFOVLSMXPWPCFH-UHFFFAOYSA-N