Description
Monobromobimane (mBBr) is a cell-permeable, thiol-reactive fluorescent probe that is widely used to detect various thiol-containing biomolecules such as glutathione in cells. It reacts rapidly at physiological pH with available thiol groups, and generates a stable fluorescent signal. Monobromobimane can be used to evaluate or quantify a variety of compounds containing reactive sulfur or thiol groups, including H2S, glutathione, proteins, and nucleotides. The excitation and emission maxima for monobromobimane are 398 and 490 nm, respectively.
Monobromobimane (mBBr) is a cell-permeable, thiol-reactive fluorescent probe that is widely used to detect various thiol-containing biomolecules such as glutathione in cells. It reacts rapidly at physiological pH with available thiol groups, and generates a stable fluorescent signal. Monobromobimane can be used to evaluate or quantify a variety of compounds containing reactive sulfur or thiol groups, including H2S, glutathione, proteins, and nucleotides. The excitation and emission maxima for monobromobimane are 398 and 490 nm, respectively.
B2672 | Monobromobimane DataSheet
Alternate Name/Synonyms: Bromobimane,NSC-608544,mBBr,NSC 608544,Bimane monobromide
Appearance: Light yellow solid
Formulation:
CAS Number: 71418-44-5
Structure Available?: Yes
Peptide sequence:
Salt Form: No
Molecular Formula: C₁₀H₁₁BrN₂O₂
Molecular Weight: 271.11
Cell-Permeable?: True
Purity: ≥98%
Solubilities: ~50 mg/ml DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A thiol-reactive fluorogenic probe
MDL Number: MFCD00036951
PubChem CID: 114810
SMILES: CC1=C(N2C(=C(C(=O)N2C1=O)C)CBr)C
InChi: InChI=1S/C10H11BrN2O2/c1-5-7(3)12-8(4-11)6(2)10(15)13(12)9(5)14/h4H2,1-3H3
InChi Key: AHEWZZJEDQVLOP-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20ºC |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |