Monobromobimane | B2672

Monobromobimane (mBBr) is a cell-permeable, thiol-reactive fluorescent probe that is widely used to detect various thiol-containing biomolecules such as glutathione in cells. It reacts rapidly at physiological pH with available thiol groups, and generates a stable fluorescent signal. Monobromobimane can be used to evaluate or quantify a variety of compounds containing reactive sulfur or thiol groups, including H2S, glutathione, proteins, and nucleotides. The excitation and emission maxima for monobromobimane are 398 and 490 nm, respectively.

Monobromobimane (mBBr) is a cell-permeable, thiol-reactive fluorescent probe that is widely used to detect various thiol-containing biomolecules such as glutathione in cells. It reacts rapidly at physiological pH with available thiol groups, and generates a stable fluorescent signal. Monobromobimane can be used to evaluate or quantify a variety of compounds containing reactive sulfur or thiol groups, including H2S, glutathione, proteins, and nucleotides. The excitation and emission maxima for monobromobimane are 398 and 490 nm, respectively.

B2672 | Monobromobimane DataSheet

Alternate Name/Synonyms: Bromobimane,NSC-608544,mBBr,NSC 608544,Bimane monobromide

Appearance: Light yellow solid

Formulation:

CAS Number: 71418-44-5

Structure Available?: Yes

Peptide sequence:

Salt Form: No

Molecular Formula: C₁₀H₁₁BrN₂O₂

Molecular Weight: 271.11

Cell-Permeable?: True

Purity: ≥98%

Solubilities: ~50 mg/ml DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A thiol-reactive fluorogenic probe

MDL Number: MFCD00036951

PubChem CID: 114810

SMILES: CC1=C(N2C(=C(C(=O)N2C1=O)C)CBr)C

InChi: InChI=1S/C10H11BrN2O2/c1-5-7(3)12-8(4-11)6(2)10(15)13(12)9(5)14/h4H2,1-3H3

InChi Key: AHEWZZJEDQVLOP-UHFFFAOYSA-N