Mouse Anti-Human MMP-12 Antibody | 101-M114

Mouse Anti-Human MMP-12 Antibody | 101-M114 | Gentaur UK, US & Europe Distribution

Species: Anti-Human

Host / biotech: Mouse

Comment: N/A

Label: N/A

Clone / Antibody feature: (#7G20)

Subcategory: Monoclonal Antibody

Category: Antibody

Synonyms: MMP12; ME; HME; MME; MMP-12

Isotype: IgG2

Application: WB, IHC (P)

Detection Range: WB: Use at 1:500-2000; IHC: 1:50-300

Species Reactivity/Cross reactivity: Human

Antigen: recombinant human MMP-12

Description: MMP12, also known as macrophage elastase, is a zinc and calcium dependent endopeptidase expressed constitutively in macrophages and can be induced in monocytes. MMP12 can degrade a broad spectrum of substrates, including type IV collagen, fibronectin, laminin, vitronectin, proteoglycans, chondroitin sulfate, myelin basic protein, α-1antitrypsin, and plasminogen. It can also activate MMP2 and MMP-3. The MMP12 precursor consists of a pro domain, a catalytic domain containing the zinc-binding site, and a C-terminal hemopexin like domain.

Purity Confirmation: N/A

Endotoxin: N/A

Formulation: lyophilized

Storage Handling Stability: Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

Reconstituation: Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Molecular Weight: N/A

Lenght (aa): N/A

Protein Sequence: N/A

NCBI Gene ID: 4321