LBD
MOUSE Bcar1 Antibody (Center) [APR04569G]
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- LBD-APR04569G
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Description
MOUSE Bcar1 Antibody (Center) [APR04569G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: M
Specificity: This MOUSE Bcar1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 322-348 amino acids from the Central region of mouse Bcar1.
Cellular Localisation: Cell junction, focal adhesion. Cytoplasm Cell projection, axon Note=Unphosphorylated form localizes in the cytoplasm (PubMed:22801373) . Localizes to focal adhesion sites following integrin engagement (PubMed:22801373) .
Molecular Weight: 94285
Clone: Polyclonal
Gene Name: Bcar1
Gene ID: 12927
Function: Docking protein which plays a central coordinating role for tyrosine kinase-based signaling related to cell adhesion (By similarity) . Implicated in induction of cell migration and cell branching (PubMed:25499443) . Involved in the BCAR3-mediated inhibition of TGFB signaling (PubMed:25499443) .
Summary: Tissue Location: Expressed in olfactory sensory neurons (at protein level) (PubMed:20881139) . Expressed abundantly in the liver, lung, brain, and at lower levels in the heart (at protein level) (PubMed:19365570) .
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Application: WB
Dilution: WB--1:1000
Synonyms: Breast cancer anti-estrogen resistance protein 1, CRK-associated substrate, p130cas, Bcar1, Cas, Crkas