Mouse Cabc1 Antibody (Center) [APR04067G]

Mouse Cabc1 Antibody (Center) [APR04067G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: M

Specificity: This Mouse Cabc1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 396-423 amino acids from the Central region of mouse Cabc1.

Cellular Localisation: Mitochondrion {ECO:0000250|UniProtKB:Q8NI60}. Membrane; Single-pass membrane protein {ECO:0000250|UniProtKB:Q8NI60, ECO:0000255}

Molecular Weight: 71743

Clone: Polyclonal

Gene Name: Coq8a {ECO:0000250|UniProtKB:Q8NI60}

Gene ID: 67426

Function: Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration (PubMed:27499294) . Its substrate specificity is unclear: does not show any protein kinase activity (PubMed:27499294) . Probably acts as a small molecule kinase, possibly a lipid kinase that phosphorylates a prenyl lipid in the ubiquinone biosynthesis pathway, as suggested by its ability to bind coenzyme Q lipid intermediates (By similarity) . Shows an unusual selectivity for binding ADP over ATP (By similarity) .

Summary: Tissue Location: Present in various tissues (at protein level) .

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Chaperone activity of bc1 complex-like, mitochondrial, Chaperone-ABC1-like, 2711-, aarF domain-containing protein kinase 3, Adck3, Cabc1