Myeloperoxidase, Human Neutrophil | 4744

Myeloperoxidase (MPO) is a hemeprotein that belongs to the XPO subfamily of the heme peroxidase superfamily.This heme protein catalyzes oxidations by hydrogen peroxide, including MPO- chloride mediated killing of microbes and tumor cells, inactivation of hemotactic factors, crosslinking of proteins and inclination of proteins.

4744 | Myeloperoxidase Human Neutrophil DataSheet

Biomolecule/Target: N/A

Synonyms: MPO, Peroxidase, myelo

Alternates names: MPO, Peroxidase, myelo

Taglines: A lysosomal protein

NCBI Gene ID #: 6351, 9560

NCBI Gene Symbol: CCL4

Gene Source: N/A

Accession #: P13236

Recombinant: No

Source: Human Neutrophil

Purity by SDS-PAGEs: 99%

Assay: SDS-PAGE

Purity: N/A

Assay #2: HPLC

Endotoxin Level: N/A

Activity (Specifications/test method): 180-220 units per mg protein after lyophilization. One unit of activity is defined as the amount of enzyme that will decompose one micromole of hydrogen peroxide per minute at 25 , pH 6.1. Reaction mixture contains 33 mM sodium phosphate, pH 6.1, 30 mM guaiacol, and 0.0012% (0.35 mM) hydrogen peroxide

Biological activity: Determined by its ability to chemoattract human blood monocytes using a concentration of 5.0-20 ng/ml.

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 150.0 kDa

Concentration: N/A

Appearance: Lyophilized protein

Physical form description: Lyophilized from 50 mM Na acetate, pH 6.0 with 100 mM NaCl

Reconstitution Instructions: Reconstitute in HO to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.

Amino acid sequence: N/A