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Myeloperoxidase, Human Neutrophil | 4744
- SKU:
- 26-4744-GEN
- Availability:
- Usually shipped in 5 working days
Description
Myeloperoxidase (MPO) is a hemeprotein that belongs to the XPO subfamily of the heme peroxidase superfamily.This heme protein catalyzes oxidations by hydrogen peroxide, including MPO- chloride mediated killing of microbes and tumor cells, inactivation of hemotactic factors, crosslinking of proteins and inclination of proteins.
4744 | Myeloperoxidase Human Neutrophil DataSheet
Biomolecule/Target: N/A
Synonyms: MPO, Peroxidase, myelo
Alternates names: MPO, Peroxidase, myelo
Taglines: A lysosomal protein
NCBI Gene ID #: 6351, 9560
NCBI Gene Symbol: CCL4
Gene Source: N/A
Accession #: P13236
Recombinant: No
Source: Human Neutrophil
Purity by SDS-PAGEs: 99%
Assay: SDS-PAGE
Purity: N/A
Assay #2: HPLC
Endotoxin Level: N/A
Activity (Specifications/test method): 180-220 units per mg protein after lyophilization. One unit of activity is defined as the amount of enzyme that will decompose one micromole of hydrogen peroxide per minute at 25 , pH 6.1. Reaction mixture contains 33 mM sodium phosphate, pH 6.1, 30 mM guaiacol, and 0.0012% (0.35 mM) hydrogen peroxide
Biological activity: Determined by its ability to chemoattract human blood monocytes using a concentration of 5.0-20 ng/ml.
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 150.0 kDa
Concentration: N/A
Appearance: Lyophilized protein
Physical form description: Lyophilized from 50 mM Na acetate, pH 6.0 with 100 mM NaCl
Reconstitution Instructions: Reconstitute in HO to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or 20°C for future use.
Amino acid sequence: N/A