Naringenin | 1772

The major flavanone found in grapefruit. Acts as an antioxidant, free radical scavenger and carbohydrate metabolism promoter. Shows cytotoxicity in various human cell lines and promotes apoptosis in rat C6 glioma model. Naringenin seems to protect LDL-receptor deficient mice from the obesity effects of a high-fat diet. Also lowers the plasma and hepatic cholesterol concentrations by suppressing HMG-CoA reductase and ACAT in rats fed with a high-cholesterol diet.

Naringenin is the major flavanone found in grapefruit. Acts as an antioxidant, free radical scavenger and carbohydrate metabolism promoter. Shows cytotoxicity in various human cell lines and promotes apoptosis in rat C6 glioma model. Naringenin seems to protect LDL-receptor deficient mice from the obesity effects of a high-fat diet.

1772 | Naringenin DataSheet

Alternate Name/Synonyms: 5,7,4'-Trihydroxyflavanone; 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; NGEN

Appearance: Brown solid

Formulation: N/A

CAS Number: 480-41-1

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₅H₁₂O₅

Molecular Weight: 272.26

Cell-Permeable?: Yes

Purity: ≥98% by TLC

Solubilities: DMSO or EtOH (50 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: An antioxidant and an ACAT inhibitor

MDL Number: MFCD00006844

PubChem CID: 932

SMILES: C1C(OC2=CC(=CC(=C2C1=O)O)O)C3=CC=C(C=C3)O

InChi: InChI=1S/C15H12O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-6,13,16-18H,7H2

InChi Key: FTVWIRXFELQLPI-UHFFFAOYSA-N