LBD
NEK11L Antibody (C-term) [APR17558G]
- SKU:
- LBD-APR17558G
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- Usually ships in 5 working days
Description
NEK11L Antibody (C-term) [APR17558G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This NEK11L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 480-510 amino acids from the C-terminal region of human NEK11L.
Cellular Localisation: Nucleus. Nucleus, nucleolus. Note=Nuclear during interphase but moves to the polar microtubules during prometaphase and metaphase (PubMed:12154088) . Accumulates in the nucleolus in G1/S-arrested cells (PubMed:15161910) .
Molecular Weight: 74192
Clone: Polyclonal
Gene Name: NEK11 (HGNC:18593)
Gene ID: 79858
Function: Protein kinase which plays an important role in the G2/M checkpoint response to DNA damage. Controls degradation of CDC25A by directly phosphorylating it on residues whose phosphorylation is required for BTRC-mediated polyubiquitination and degradation.
Summary: Tissue Location: Poorly expressed in cerebellum, trachea, lung, appendix, and uterus.
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB
Dilution: WB--1:1000
Synonyms: Serine/threonine-protein kinase Nek11, Never in mitosis A-related kinase 11, NimA-related protein kinase 11, NEK11 (HGNC:18593)