NKX2.1 Antibody (TTF1)| F40894-0.08ML

NKX2.1 Antibody (TTF1)| F40894-0.08ML | Gentaur UK, US & Europe Distribution

Background: This gene encodes a protein initially identified as a thyroid-specific transcription factor. NKX2.1/TTF1 binds to thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Human

Predicted Spacies Reactivity: Mouse, Rat

Application: WB, FACS, ELISA

Application Details: Western blot: 1:1000, Flow Cytometry: 1:10-1:50

Application Note: Titration of the TTF1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This TTF1 antibody is available for research use only.

Purity: Antigen affinity

Immunogen: A portion of amino acids 2-1 from the human protein was used as the immunogen for this TTF1 antibody.

Storage: Aliquot the TTF1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A