Description
NLG919 is a potent inhibitor of indoleamine-2,3-dioxygenase (IDO)-pathway (Ki = 7 nM). Indoleamine 2,3-dioxygenase (IDO) is an enzyme with immune-suppressive properties that is commonly exploited by tumors to evade immune destruction.
NLG919 is a potent inhibitor of indoleamine-2,3-dioxygenase (IDO)-pathway (Ki = 7 nM). Indoleamine 2,3-dioxygenase (IDO) is an enzyme with immune-suppressive properties that is commonly exploited by tumors to evade immune destruction.
Alternate Name/Synonyms: 1-cyclohexyl-2-(5H-imidazo[5,1-a]isoindol-5-yl)ethanol; NLG-919
Appearance: Off-white solid
Formulation: N/A
CAS Number: 1402836-58-1
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₈H₂₂N₂O
Molecular Weight: 282.38
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (~ 3 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent inhibitor of indoleamine-2,3-dioxygenase (IDO)-pathway inhibitor
MDL Number: N/A
PubChem CID: 66558287
SMILES: C1CCC(CC1)C(CC2C3=CC=CC=C3C4=CN=CN24)O
InChi: InChI=1S/C18H22N2O/c21-18(13-6-2-1-3-7-13)10-16-14-8-4-5-9-15(14)17-11-19-12-20(16)17/h4-5,8-9,11-13,16,18,21H,1-3,6-7,10H2
InChi Key: YTRRAUACYORZLX-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |