NLG919 | 9407

NLG919 is a potent inhibitor of indoleamine-2,3-dioxygenase (IDO)-pathway (Ki = 7 nM). Indoleamine 2,3-dioxygenase (IDO) is an enzyme with immune-suppressive properties that is commonly exploited by tumors to evade immune destruction.

NLG919 is a potent inhibitor of indoleamine-2,3-dioxygenase (IDO)-pathway (Ki = 7 nM). Indoleamine 2,3-dioxygenase (IDO) is an enzyme with immune-suppressive properties that is commonly exploited by tumors to evade immune destruction.

9407 | NLG919 DataSheet

Alternate Name/Synonyms: 1-cyclohexyl-2-(5H-imidazo[5,1-a]isoindol-5-yl)ethanol; NLG-919

Appearance: Off-white solid

Formulation: N/A

CAS Number: 1402836-58-1

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₈H₂₂N₂O

Molecular Weight: 282.38

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (~ 3 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent inhibitor of indoleamine-2,3-dioxygenase (IDO)-pathway inhibitor

MDL Number: N/A

PubChem CID: 66558287

SMILES: C1CCC(CC1)C(CC2C3=CC=CC=C3C4=CN=CN24)O

InChi: InChI=1S/C18H22N2O/c21-18(13-6-2-1-3-7-13)10-16-14-8-4-5-9-15(14)17-11-19-12-20(16)17/h4-5,8-9,11-13,16,18,21H,1-3,6-7,10H2

InChi Key: YTRRAUACYORZLX-UHFFFAOYSA-N