NLRP10 Antibody| F43011-0.08ML/F43011-0.4ML

NLRP10 Antibody| F43011-0.08ML/F43011-0.4ML | Gentaur UK, US & Europe Distribution

Background: Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs to the NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as a multifunctional negative regulator of inflammation and apoptosis. [provided by RefSeq].

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Human

Predicted Spacies Reactivity: N/A

Application: WB, ELISA

Application Details: Western blot: 1:1000

Application Note: Titration of the NLRP10 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This NLRP10 antibody is available for research use only.

Purity: Antigen affinity

Immunogen: A portion of amino acids 466-494 from the human protein was used as the immunogen for this NLRP10 antibody.

Storage: Aliquot the NLRP10 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A