Description
nor-NOHA acetate is a potent, reversible inhibitor of rat liver arginase with a Ki value of 0.5 µM, which is 20-fold lower than the Ki of 10 µM observed for NOHA. Nor-NOHA is about 40-fold more potent than NOHA as an inhibitor of arginase from mouse macrophages, displaying an IC₅₀ of 10-12 µM.
nor-NOHA acetate is a potent, reversible inhibitor of rat liver arginase with a Ki value of 0.5 µM, which is 20-fold lower than the Ki of 10 µM observed for NOHA. Nor-NOHA is about 40-fold more potent than NOHA as an inhibitor of arginase from mouse macrophages, displaying an IC₅₀ of 10-12 µM.
B2550 | nor-NOHA acetate DataSheet
Alternate Name/Synonyms: Nω-hydroxy-nor-Arginine; 2S-amino-4-[[(hydroxyamino)iminomethyl]amino]-butanoic acid, diacetate
Appearance: Lyophilized solid
Formulation:
CAS Number: 1140844-63-8
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₅H₁₂N₄O₃ • 2C₂H₄O₂
Molecular Weight: 296.3
Cell-Permeable?: True
Purity: ≥97%
Solubilities: ~ 5 mg/ml in DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A potent, selective, and high affinity arginase inhibitor
MDL Number:
PubChem CID: 16760508
SMILES: CC(=O)O.CC(=O)O.C(CN=C(N)NO)C(C(=O)O)N
InChi: InChI=1S/C5H12N4O3.2C2H4O2/c6-3(4(10)11)1-2-8-5(7)9-12;2*1-2(3)4/h3,12H,1-2,6H2,(H,10,11)(H3,7,8,9);2*1H3,(H,3,4)/t3-;;/m0../s1
InChi Key: PQFYTZJPYBMTCT-QTNFYWBSSA-N
Additional Information
Storage Condition: |
-20ºC |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |