nor-NOHA acetate | B2550

nor-NOHA acetate is a potent, reversible inhibitor of rat liver arginase with a Ki value of 0.5 µM, which is 20-fold lower than the Ki of 10 µM observed for NOHA. Nor-NOHA is about 40-fold more potent than NOHA as an inhibitor of arginase from mouse macrophages, displaying an IC₅₀ of 10-12 µM.

nor-NOHA acetate is a potent, reversible inhibitor of rat liver arginase with a Ki value of 0.5 µM, which is 20-fold lower than the Ki of 10 µM observed for NOHA. Nor-NOHA is about 40-fold more potent than NOHA as an inhibitor of arginase from mouse macrophages, displaying an IC₅₀ of 10-12 µM.

B2550 | nor-NOHA acetate DataSheet

Alternate Name/Synonyms: Nω-hydroxy-nor-Arginine; 2S-amino-4-[[(hydroxyamino)iminomethyl]amino]-butanoic acid, diacetate

Appearance: Lyophilized solid

Formulation:

CAS Number: 1140844-63-8

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₅H₁₂N₄O₃ • 2C₂H₄O₂

Molecular Weight: 296.3

Cell-Permeable?: True

Purity: ≥97%

Solubilities: ~ 5 mg/ml in DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A potent, selective, and high affinity arginase inhibitor

MDL Number:

PubChem CID: 16760508

SMILES: CC(=O)O.CC(=O)O.C(CN=C(N)NO)C(C(=O)O)N

InChi: InChI=1S/C5H12N4O3.2C2H4O2/c6-3(4(10)11)1-2-8-5(7)9-12;2*1-2(3)4/h3,12H,1-2,6H2,(H,10,11)(H3,7,8,9);2*1H3,(H,3,4)/t3-;;/m0../s1

InChi Key: PQFYTZJPYBMTCT-QTNFYWBSSA-N