NOX4 Antibody| F43447-0.08ML/F43447-0.4ML/R31029

NOX4 Antibody| F43447-0.08ML/F43447-0.4ML/R31029 | Gentaur UK, US & Europe Distribution

Background: This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Human

Predicted Spacies Reactivity: N/A

Application: WB, IHC, ELISA

Application Details: Western blot: 1:1000, IHC (Paraffin): 1:10-1:50

Application Note: Titration of the NOX4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This NOX4 antibody is available for research use only.

Purity: Antigen affinity

Immunogen: A portion of amino acids 124-153 from the human protein was used as the immunogen for this NOX4 antibody.

Storage: Aliquot the NOX4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A