Description
NSC-207895 is a cell-permeable benzofuroxan derivative that acts as a MDMX inhibitor (IC₅₀ = 2.5 µM). Activates p53 and induces apoptosis in cancer cells. Active in vitro and in vivo.
NSC-207895 is a cell-permeable benzofuroxan derivative that acts as a MDMX inhibitor (IC₅₀ = 2.5 µM). Activates p53 and induces apoptosis in cancer cells. Active in vitro and in vivo.
Alternate Name/Synonyms: 7-(4-Methylpiperazin-1-yl)-4-nitro-2,1,3-benzoxadiazole-1-oxide
Appearance: Dark red solid
Formulation: N/A
CAS Number: 58131-57-0
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₁H₁₃N₅O₄
Molecular Weight: 279.25
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (>0.4 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent MDMX inhibitor
MDL Number: N/A
PubChem CID: 42640
SMILES: CN1CCN(CC1)C2=CC=C(C3=NO[N+](=C23)[O-])[N+](=O)[O-]
InChi: InChI=1S/C11H13N5O4/c1-13-4-6-14(7-5-13)9-3-2-8(15(17)18)10-11(9)16(19)20-12-10/h2-3H,4-7H2,1H3
InChi Key: MWFZDJLPWDCQIL-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |