NSC-207895 | B1228

NSC-207895 is a cell-permeable benzofuroxan derivative that acts as a MDMX inhibitor (IC₅₀ = 2.5 µM). Activates p53 and induces apoptosis in cancer cells. Active in vitro and in vivo.

NSC-207895 is a cell-permeable benzofuroxan derivative that acts as a MDMX inhibitor (IC₅₀ = 2.5 µM). Activates p53 and induces apoptosis in cancer cells. Active in vitro and in vivo.

B1228 | NSC-207895 DataSheet

Alternate Name/Synonyms: 7-(4-Methylpiperazin-1-yl)-4-nitro-2,1,3-benzoxadiazole-1-oxide

Appearance: Dark red solid

Formulation: N/A

CAS Number: 58131-57-0

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₁H₁₃N₅O₄

Molecular Weight: 279.25

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (>0.4 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent MDMX inhibitor

MDL Number: N/A

PubChem CID: 42640

SMILES: CN1CCN(CC1)C2=CC=C(C3=NO[N+](=C23)[O-])[N+](=O)[O-]

InChi: InChI=1S/C11H13N5O4/c1-13-4-6-14(7-5-13)9-3-2-8(15(17)18)10-11(9)16(19)20-12-10/h2-3H,4-7H2,1H3

InChi Key: MWFZDJLPWDCQIL-UHFFFAOYSA-N